A Food and Drug Administration rule implemented in December 2000 mandates that any new drug that they intend to be used both by adults and children must undergo pediatric study and that its manufactures list children’s doses on the label. 


A. drug that they intend to be used both by adults and children must


B. drug whose intended use is for adults and children as well


C. drug intended for use by both adults and children


D. drug, if they intend that it be used by adults and also children, must


E. drug, if intended for use both by adults and children, must



The first clue in the sentence is- F and D Administration rule implemented in December 2000 mandates that any new drug


The use of mandates that - subjunctive

Present subjunctives should be followed by a verb in its base form. 


A Food and Drug Administration rule implemented in December 2000 mandates that any new drug….  undergo (verb in its base form) pediatric study…

This means that any option that uses- must undergo/ should undergo or to undergo should be eliminated- Eliminate A, D, and E. 


B. drug whose intended use is for adults and children as well

This means that the primary use is for adults and then children as well. This brings in an issue with meaning.


C. drug intended for use by both adults and children


Option C is the most appropriate answer.